Trimetazidine is used for long term treatment of angina. Angina is chest pain arising from the heart muscle when it does not receive enough oxygen. You may have the feeling of indigestion, fullness, pressure or tightness in the chest spreading to your arms or neck.

Trimetazidine is a cytoprotective drug that normalizes metabolic disturbances in low-flow ischemia via several not yet fully understood mechanisms of action. The best known trimetazidine mechanism of action is its capacity to inhibit -oxidation of free fatty acid.